Geistlich Biomaterials introduces the first xenogeneic/allogeneic validated bone substitute

Setting the standard in regenerative materials, Geistlich Biomaterials has developed ground-breaking product innovations in hard and soft tissue highlighted by Geistlich Bio-Oss®, Geistlich Bio-Gide® and Geistlich Fibro-Gide®. Now, Geistlich Biomaterials is taking another step combining two validated1 regenerative materials for restoring vital bone faster2 – with proven long-term volume stability3-8.

Geistlich Biomaterials has introduced the first xenogeneic/ allogeneic validated bone substitute1, Geistlich vallomix™, which conveniently co-packages vallos™, a demineralised cortical allograft and Geistlich Bio-Oss® the leading xenogeneic bone substitute worldwide, with more than 35 years of scientific research.

Verified vallos™ granules and fibres are allogeneic bone substitutes that have been demineralised to ensure high osteoinductive properties1. A demineralised bone matrix has the advantage of turning over natural bone more rapidly but lacks the volume stability needed in several clinical situations9.

Geistlich Bio-Oss® ensures a treatment solution with demonstrated clinical success, an optimal scaffold for vascularisation and new bone formation, and long-term volume stability3-8.

Together, Geistlich vallomix™ offers optimal consistency and performance in demanding clinical situations1-14.


  1. Compiled DCI Osteoinductivity Validation Summary_2020. (data on file)
  2. Robert A Wood & Brian L Mealey: J Periodontol. 2012 Mar;83(3):329-36. (Clinical Study)
  3. Piattelli M et al.: Int J Oral Maxillofac Implants 1999; 14 (6), 835-40. (Clinical Study).
  4. Sartori S et al.: Clin Oral Implants Res 2003; 14 (3), 369-72. (Clinical Study).
  5. Maiorana C et al.: Int J Periodontics Restorative Dent 2005; 25 (1), 19-25. (Clinical Study).
  6. Orsini G et al.: Oral Dis 2007; 13 (6), 586-93. (Clinical Study).
  7. Lindgren C et al.: Int J Oral Maxillofac Implants 2009; 24 (6), 1093-100. (Clinical Study).
  8. Mordenfeld A et al.: Clin Oral Implants Res 2010; 21 (9), 961-70. (Clinical Study).
  9. Serrano CA et al.: Implant Dent. 2018 Aug; 27(4):467-473. (Clinical Study).
  10. 10.NCBI Pubmed, Month Year, Search term “Bio-Oss” (1208 hits) (Market research).
  11. Berglundh T & Lindhe J: Clin Oral Implants Res 1997; 8 (2), 117-24. (Preclincal Study).
  12. Weibrich G et al.: Mund Kiefer Gesichtschir 2000; 4 (3), 148-52. (Preclincal Study).
  13. Degidi M et al.: Oral Dis 2006; 12 (5), 469-75. (Clinical Study).
  14. Galindo-Moreno P et al.: Clin Oral Implants Res 2010; 21 (2), 221-7. (Clinical Study).